We are a chemical biology laboratory focused on the development of technologies to map molecules, cells, and functional circuits. We apply the technologies to understand signaling in the mitochondria and mammalian brain.
Our technologies draw from protein engineering, directed evolution, chemical synthesis, high-resolution microscopy, genetics, and computational analysis.
Neuroscientists need ever-more specific methods to restrict expression of tools to defined neuronal subpopulations.… https://t.co/dygy9E27fp
This review on “Molecular tools for imaging and recording neuronal activity” was really fun to write with postdoc c… https://t.co/ImNQYC1wCE
Clever strategy for detecting & studying protein-protein interactions in the membranes of living cells. Immobilize… https://t.co/P1ru7oOx4m
Orthogonal ribosome platform in E. coli enables evolution of ribosome mutant that translates polyPro sequences, whi… https://t.co/WEmMgADrmE