We are a chemical biology laboratory focused on the development of technologies to map molecules, cells, and functional circuits. We apply the technologies to understand signaling in the mitochondria and mammalian brain.
Our technologies draw from protein engineering, directed evolution, chemical synthesis, high-resolution microscopy, genetics, and computational analysis.
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How do RNA granules move around in cells & neurons? By hitching a ride on lysosomes (via the adaptor protein ANXA11… https://t.co/GAYL30bO8h
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UPenn undergrads Krishna Suresh & Sumant Shringari shared with me their class video project covering our PNAS paper… https://t.co/WscXrxpdGA
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RT @omgtinakim: Out today in @eLife! My first PD paper with @aliceyting, and my first foray into protein engineering. Rather than u… https://t.co/ZYxbXq2hF3
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Our paper is out at eLife, showing that Luciferase can regulate the LOV domain via BRET. We used this to toggle bw… https://t.co/UdkyDhRBPD