We are a chemical biology laboratory focused on the development of technologies to map molecules, cells, and functional circuits. We apply the technologies to understand signaling in the mitochondria and mammalian brain.
Our technologies draw from protein engineering, directed evolution, chemical synthesis, high-resolution microscopy, genetics, and computational analysis.
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Exciting advance from lab of Peng Zou at PKU: biotin-aniline is a superior substrate to biotin-phenol for APEX-seq… https://t.co/qGdc8tp0kw
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New NIH/NIA RFA just announced today seeking proposals to combine chemical biology approaches (APEX, BioID, BONCAT,… https://t.co/wywmrTbNlK
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Was so excited & impressed to learn about these fully synthetic programmable RNA binding proteins (“artificial Cas1… https://t.co/muIFpx3F3i
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"APEX-seq" for spatial transcriptomics in living cells, via APEX-catalyzed proximity labeling of RNAs. Beautiful co… https://t.co/tVKjnx27jf